Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Systematic review of fondaparinux for heparin-induced thrombocytopenia: When there are no randomized controlled trials Linkins L, Hu G, Warkentin TE 2018 Res Pract Thromb Haemost View Researchers Clinical research
A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss Sheffield WP, Eltringham-Smith LJ, Bhakta V 2018 BMC Biotechnol View Researchers Basic research
Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex Kipkeu BJ, Almizraq R, Branch DR, Acker JP, Holovati JL 2018 ISBT Sci Ser View Researchers Basic research
ResearchUnit: Platelet protein GPIba plays an important role in regulating platelet-mediated production of thrombopoietin by the liver Ni H 2018 Blood.ca website View Other Other
Troubles de l'hémostase et angioedéme héréditaire Poon MC, Goodyear MD, Rydz N, Lee A 2018 Guide de la pratique transfusionnelle View Health care providers Other
Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment Tseng EK, Jo D, Shih AW, De Wit K, Chan TM 2018 AEM Educ Train View Researchers Education research
Anti-D; a type of IVIg Khan R, Lazarus A 2018 Antibody Therapy: Substitution - Immunomodulation - Monoclonal Immunotherapy View Health care providers Other
Rivaroxaban and Apixaban induce clotting factor Xa fibrinolytic activity Carter RLR, Talbot K, Hur WS, Meixner SC, Van Der Gugten JG, Holmes DT, Côté HCF, Kastrup CJ, Smith TW, Lee AYY, Pryzdial ELG 2018 J Thromb Haemost View Health care providers Basic research
The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A 2018 Clin Biochem View Researchers Basic research
Synthesis of Highly Biocompatible and Temperature-Responsive Physical Gels for Cryopreservation and 3D Cell Culture Nagao M, Sengupta J, Diaz-Dussan D, Adam M, Wu M, Acker J, Ben R, Ishihara K, Zeng H, Miura Y, Narain R 2018 ACS Appl Bio Mater View Researchers Basic research
Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use Lin Y, Cohen R, Armali C, Callum J, Cserti-Gazdewich C, Lieberman L, Pendergrast J 2018 Vox Sang View Researchers Clinical research
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA 2018 Blood Adv View Researchers Basic research
Albumin Clarke G, Yan M 2018 Clinical Guide to Transfusion View Health care providers Other
McMaster RARE-Best practices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome Legault K, Schunemann H, Hillis C, Yeung C, Akl EA, Carrier M, Cervera R, Crowther M, Dentali F, Erkan D, Espinosa G, Khamashta M, Meerpohl JJ, Moffat K, O'Brien S, Pengo V, Rand JH, Rodriguez Pinto I, Thom L, Iorio A 2018 J Thromb Haemost View Health care providers Benchmarking and standard setting
Designing the blood supply chain: how much, how and where? Osorio AF, Brailsford SC, Smith HK, Blake J 2018 Vox Sang View Other New or improved product or process
Questioning some recommendations in the umbilical cord blood guideline Elmoazzen H, Petraszko T 2018 J Obstet Gynaecol Can View Health care providers New or improved product or process
ResearchUnit: A model for change: predicting the impact of system-wide improvements Blake J 2018 Blood.ca website View Other New or improved product or process
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process
Anti-M (French) Clarke G, Cote J, Lane D 2018 Blood.ca website View Researchers Basic research
Cyclic thrombocytopenia with statistically significant neutrophil oscillations Langlois GP, Arnold DM, Potts J, Leber B, Dale DC, Mackey MC 2018 Clin Case Rep View Health care providers Clinical research
Low platelet count as risk factor for infections in patients with primary immune thrombocytopenia: a retrospective evaluation Qu M, Liu Q, Zhao H-G, Peng J, Ni H, Hou M, Jansen AJG 2018 Ann Hematol View Health care providers Clinical research
Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort Feldman BM, Rivard GE, Babyn P, Wu JKM, Steele M, Poon M-C, Card RT, Israels SJ, Laferriere N, Gill K, Chan AK, Carcao M, Klaassen RJ, Cloutier S, Price VE, Dover S, Blanchette VS 2018 Lancet Haematol View Health care providers Clinical research
Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques Jenkins C 2018 Blood.ca website View Health care providers Benchmarking and standard setting
The effect of unmeasurable endogenous plasma factor activity levels on factor VIII dosing in patients with severe hemophilia A McEneny-King A, Chelle P, Iorio A, Edginton AN 2018 Thromb Res View Health care providers Clinical research
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D 2018 Am J Hosp Palliat Care View Researchers Clinical research
Erythrocyte saturation with IgG is required for inducing antibody-mediated immune suppression and impacts both erythrocyte clearance and antigen-modulation mechanisms Cruz-Leal Y, Marjoram D, Lazarus AH 2018 J Immunol View Researchers Basic research
ResearchUnit: Patient blood group impacts susceptibility to IVIg-associated hemolysis Branch D 2018 Blood.ca website View Researchers Basic research
A Deep Learning Method to Automatically Identify Reports of Scientifically Rigorous Clinical Research from the Biomedical Literature: Comparative Analytic Study Del Fiol G MM, Iorio A, Cotoi C, Haynes RB 2018 J Med Internet Res View Researchers Clinical research
Circular of information for the use of human blood components: Platelets Jenkins C 2018 Blood.ca website View Health care providers Benchmarking and standard setting
Aphérèse thérapeutique Pavenski K 2018 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM 2018 Transfusion View Researchers Clinical research
Plerixafor effectively mobilizes CD56bright NK cells in blood, providing an allograft predicted to protect against GVHD Wong PPC, Kariminia A, Jones D, Eaves CJ, Foley R, Ivison S, Couban S, Schultz KR 2018 Blood View Health care providers Clinical research
Signalement des réactions transfusionnelles indésirables Chargé S, Young D 2018 Blood.ca website View Health care providers Other
Evaluation of the functional properties of cryopreserved buffy coat-derived monocytes for monocyte monolayer assay Kipkeu BJ, Shyian ML, da Silveira Cavalcante L, Duong TT, Yeung RSM, Binnington B, Branch DR, Acker JP, Holovati JL 2018 Transfusion View Researchers Basic research
Concentré de recherche: Important rôle de la GPIba, une protéine plaquettaire, dans la régulation de la production hépatique de thrombopoiétine Ni H 2018 Blood.ca website View Other Other
Concentrates for Hemostatic Disorders and Hereditary Angioedema Poon MC, Goodyear MD, Rydz N, Lee A 2018 Clinical Guide to Transfusion View Health care providers Other
Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31) Turley E, McGowan EC, Hyland CA, Schoeman EM, Flower RL, Skoll A, Delisle MF, Nelson T, Clarke G, Au N 2018 Transfusion View Researchers Clinical research
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med View Researchers Clinical research
IgA deficiency Goldman M 2018 Blood.ca website View Health care providers Benchmarking and standard setting
The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallee LT, Fergusson DA, Breau RH 2018 Transfus Med Rev View Researchers Clinical research
Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther M, Iorio A 2018 BMJ Open View Researchers Clinical research
Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW 2018 Scand J Immunol View Researchers Basic research
How do we diagnose immune thrombocytopenia in 2018? Kelton JG VJ, Arnold DM 2018 Hematology Am Soc Hematol Educ Program View Health care providers Clinical research
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Pierce GF, Iorio A 2018 Haemophilia View Health care providers New or improved product or process
Concurrence of symmetrical peripheral gangrene and venous limb gangrene following polytrauma: a case report Tan JH, Mohamad Y, Tan CLH, Kassim M, Warkentin TE 2018 J Med Case Rep View Health care providers Clinical research
Transfusion Safety: The Nature and Outcomes of Errors in Patient Registration Cohen R, Ning S, Yan MTS, Callum J 2018 Transfus Med Rev View Health care providers Clinical research
Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations Iorio A, Edginton AN, Blanchette V, Blatny J, Boban A, Cnossen M, Collins P, Croteau SE, Fischer K, Hart DP, Ito S, Korth-Bradley J, Lethagen S, Lillicrap D, Makris M, Mathôt R, Morfini M, Neufeld EJ, Spears J 2018 Res Pract Thromb Haem View Health care providers Clinical research
Hommes gais et don de sang : Un projet à  l'étude Otis J, Caruso J 2018 Fugues View Other Other
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I 2018 Chest View Researchers Basic research
A multicentred study to validate a consensus bleeding assessment tool developed by the biomedical excellence for safer transfusion collaborative for use in patients with haematological malignancy Dyer C, Alquist CR, Cole-Sinclair M, Curnow E, Dunbar NM, Estcourt LJ, Kaufman R, Kutner JM, McCullough J, McQuilten Z, Potiphar L, Rioux-Masse B, Slichter S, Tinmouth A, Webert K, Yokoyama AP, Stanworth SJ 2018 Vox Sang View Health care providers Clinical research