Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances McVey MJ, Cohen R, Arsenault V, Escorcia A, Tasmin F, Pendergrast J, Lieberman L, Lin Y, Callum J, Cserti-Gazdewich C 2021 Vox Sang View Health care providers Clinical research
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant Hamada M, Bhakta V, Andres SN, Sheffield WP 2021 Front Cardiovasc Med View Researchers Basic research
International Forum on Walking Blood Bank Programmes: Responses Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N 2021 Vox Sang View Blood operators New or improved product or process
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T 2021 Blood View Researchers Clinical research
Spontaneous HIT syndrome: Knee replacement, infection, and parallels with vaccine-induced immune thrombotic thrombocytopenia Warkentin TE, Greinacher A 2021 Thromb Res View Researchers Clinical research
Early warning and rapid public health response to prevent COVID-19 outbreaks in long-term care facilities (LTCF) by monitoring SARS-CoV-2 RNA in LTCF site-specific sewage samples and assessment of antibodies response in this population: prospective study protocol Lee BE, Sikora C, Faulder D, Risling E, Little LA, Qiu Y, Gao T, Bulat R, Craik S, Hrudey SE, Ohinmaa A, Estabrooks CA, Gingras A-C, Charlton C, Kim J, Wood H, Robinson A, Kanji JN, Zelyas N, O’Brien SF, Drews S, Pang X-L 2021 BMJ Open View Regulators New or improved product or process
Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity Himbert S, Qadri SM, Sheffield WP, Schubert P, D’Alessandro A, Rheinstädter MC 2021 PLoS One View Researchers Basic research
Venous Thromboembolism and Mild Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination Gabarin N, Patterson S, Pai M, Afzaal T, Nazy I, Sheppard JI, Arnold DM, Warkentin TE 2021 Thromb Haemost View Health care providers Clinical research
Buffy coat platelets coming to America: Are we ready? Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R 2021 Transfusion View Blood operators New or improved product or process
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B 2021 Intensive Care Med Researchers Clinical research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion Leatherdale A, Parker DA, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM 2021 J Thromb Haemost View Researchers Basic research
Research initiatives of blood services worldwide in response to the covid-19 pandemic O'Brien SF, Lieshout-Krikke RW, Lewin A, Erikstrup C, Steele WR, Uzicanin S, Custer B, the Surveillance RA, Policy Sub-group of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2021 Vox Sang View Researchers Clinical research
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins CC, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates SM, Lang E, Le Gal G, Haramati LB, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa RA 2021 Blood Adv View Researchers Clinical research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I 2021 Viruses View Researchers Clinical research
An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study Germain M, Grégoire Y, Custer BS, Goldman M, Bravo M, Kamel H, Davison K, Field S, van den Hurk K, van de Laar TJW, Irving DO, Jones A, Liumbruno G, Morley S, O’Brien SF, Pillonel J, Steinsvåg CT, Takanashi M, Tsuno NH, Vesga Carasa MA, Wendel S, Vassallo RR, Tiberghien P, for the BEST Collaborative 2021 Vox Sang View Researchers Benchmarking and standard setting
Circulaire d'information utilisation de composants sanguins humains: Plaquettes Jenkins C 2021 Blood.ca website Health care providers Benchmarking and standard setting
Concentré de recherche: L’administration d’albumine par voie intraveineuse ne conduit pas à de meilleurs résultats chez les personnes subissant des opérations cardiaques Bartoszko J 2021 Blood.ca website View Health care providers Clinical research
Screening of Feijoa (Acca Sellowiana (O. Berg) Burret) Fruit Effect on Proliferation and Apoptosis using Bone Marrow derived Stem Cells Model Rasekh H, Mahrabani D, Hosseini Farahi M, Masoumi S, Acker J 2021 Electron J Gen Med View Researchers Basic research
Determinants of the intention to participate in a programme of plasma donation for fractionation among men who have sex with men Veillette-Bourbeau L, Otis J, Lewin A, Godin G, Germain M, Daunais-Laurin G, Lalonde F, Caruso J, Myhal G, Pronovost F 2021 Vox Sang View Researchers MSM research
Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia Shen C, Liu M, Mackeigan DT, Chen ZY, Chen P, Karakas D, Li J, Norris PAA, Li J, Deng Y, Long C, Lai R, Ni H 2021 Arch Toxicol View Researchers Basic research
Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Choi P, Althaus K, Ahlen MT, Sharma R, Grace RF, Bakchoul T 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
Aspirin nonsensitivity in patients with vascular disease: Assessment by light transmission aggregometry (aspirin nonsensitivity in vascular patients) Khan H, Zamzam A, Gallant RC, Syed MH, Rand ML, Ni H, Forbes TL, Al-Omran M, Qadura M 2021 Res Pract Thromb Haemost View Researchers Clinical research
Chapitre 2: Les composants sanguins Gupta A, Bigham M 2021 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Responses Goldman M, Townsend M, Magnussen K, Lozano M, Nissen-Meyer LSH, Lee CK, Leung JN, Takanashi M, McKay J, Kvist M, Robitaille N, Deschênes J, Di Angelantonio E, McMahon A, Roberts D, Maghsudlu M, Castrén J, Tiberghien P, Woimant G, Morel P, Kamel H, Bravo M, Shinar E, Gendelman V, Raz H, Wendel S, Fachini R, Quee F, van den Hurk K, Wiersum J, Grima KM, Speedy J, Bruun MT, Dunbar NM 2021 Vox Sang View Health care providers Benchmarking and standard setting
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W 2021 Adv Ther View Researchers Clinical research
Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology Sirotich E, Guyatt G, Gabe C, Ye Z, Beck CE, Breakey V, Cooper N, Cuker A, Charness J, de Wit K, DiRaimo J, Fein SG, Grace RF, Hassan Z, Jamula E, Kang M, Manski CF, O'Connor C, Pai M, Paynter D, Porter SC, Pruitt B, Strachan G, Webert KE, Yan JW, Kelton JG, Bakchoul T, Arnold DM 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
Risk of transfusion-transmitted Babesia microti in Canada O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G 2021 Transfusion View Researchers Benchmarking and standard setting
Réactions transfusionnelles anaphylactiques et déficit en IgA Khandelwal A, Clarke G, Goldman M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Factors associated with wrong blood in tube errors: An international case series - The BEST collaborative study Dunbar NM, Kaufman RM 2021 Transfusion View Health care providers Benchmarking and standard setting
A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia Rubino JG, Arnold DM, Warkentin TE, Smith JW, Kelton JG, Nazy I 2021 J Thromb Haemost View Researchers Basic research
Monocyte monolayer assay predictions of clinical outcome for serologically incompatible red blood cells is all about timing Branch DR, Sandhu G, Raos M 2021 Transfusion View Researchers New or improved product or process
Donor screening question alternatives to men who have sex with men time deferral: Potential impact on donor deferral and discomfort O'Brien SF, Goldman M, Robillard P, Osmond L, Myhal G, Roy É 2021 Transfusion View Blood operators MSM research
Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation Yang X, Toyofuku WM, Scott MD 2021 Arch Immunol Ther Exp View Researchers Basic research
Anemia-Induced Bleeding in Patients with Platelet Disorders Thakar S, Gabarin N, Gupta A, Radford M, Warkentin TE, Arnold DM 2021 Transfus Med Rev View Health care providers Clinical research
Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet Liu M, Wang G, Xu R, Shen C, Ni H, Lai R 2021 Molecules View Researchers Basic research
Degradation of red blood cell deformability during cold storage in blood bags Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Scott MD, Ma H 2021 eJHaem View Researchers Basic research
Patterns of joint damage in severe haemophilia A treated with prophylaxis Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM 2021 Haemophilia View Health care providers Clinical research
Qualitative study to support the content validity of the immune thrombocytopenia (ITP) Life Quality Index (ILQI) Cooper N, Cuker A, Bonner N, Ghanima W, Provan D, Morgan M, Taylor B, D'Alessio D, Arnold D, Viana R 2021 Br J Haematol View Health care providers Benchmarking and standard setting
Trauma 2021: Trauma Association of Canada Annual Scientific Meeting, Vancouver, British Columbia (virtual), April 12–16, 2021 Bednarek O, O’Leary M, Hurley S, Cummings C, Bird R, Frattini S, McEachern S, Benjamin S, Pereira A, Brigode W, MacLean A, Moore L, Makish A, Sadler J, Sadler J, Albacete S, Forbes H, Grzelak S, Strauss R, Strauss R, Upadhyaya Y, Leung V, Tropiano J, Moore M, Greene J, Goldstein J, Schmitz E, Bratu I, Alballa AS, Dawe P, Malone J, Javidan AP, Allen L, Curtis RM, Ssebazza K, Schellenberg M, Lampron J, Tanenbaum B, Chisholm A, Ringuette J, Watson I, Shi D, Bhangu A, Moffat B, Fong D, Moore L, Farquharson S, Al Khaboori S, Lorthios-Guilledroit A, Côté C, McPherson J, Tran A, Guttman M, Yeung M, Poirier R-A, Siddiqi M, Evans T, Guiab K, Guiab K, Bradley N, Elliott C, Bradley N, Power A, Kirkpatrick A, Merkle A, Jessula S, Minor S, Emsley J, Sameoto C, Fitzpatrick E, Erdogan M, Lampron J, Green R, Sibley A, Jain T, Nicholson B, Stryhn H, Karsli C, Stuhler R, Ng E, Coates A, Engels P, Benjamin S, Watson I, Watson I, Talsma AN, Lobchuk M, Thongpriwan V, Cahill S, Mis J, Starr F, Bokhari F, Ladak A, Snelgrove R, Wang H, Power H, Bradley N, Allen L, Leeper R, Parry N, Ball I, Vogt K, Moffat B, Rawls D, Dawe P, Ramler G, Andres E, Rawls D, Lakha N, Brisson A, Merchant J, Forbes H, Widder S, Bradley N, Bradley N, Widder S, Albacete S, Berube M, Gagnon M-A, Pelet S, Belzile É, Kron A, Callum J, Armali C, Modi D, Notario L, Perez P, Tillmann B, Pannell D, Beckett A, Tien H, Nathens A, Da Luz L, Perrier L, Menchetti I, Blondal E, Peng H, Sullivan-Kwantes W, Tien H, Nathens A, Beckett A, Callum J, Da Luz L, Irfan N, Coates A, Engels P, Razek T, Wilson A, Beckett A, Goltz D, Figueira S, Knight H, Lampron J, Devine D, Callum J, Jenkins C, Beckett A, Goldstien J, Leroux Y, McVey J, Brown R, Swain J, Carter A, Fidgen D, Baker S, Butts F, McCulloch S, Opra I, Jensen J, Travers A, Andreou P, Earl M, Warner G, Carter A, Rezaaifar M, Figueira S, Wilkins D, Lampron J, Lai K, Hafeez AA, Goldberg S, Abahuje E, Pozner C, Yule S, Parker S, Dias R, Simons R, Joos E, Haines VV, Linder J, Cameron A, Nathens A, Cleghorn G, Chaplin T, Vogt K, Parry N, Priestap F, Leeper R, Mujoomdar A, Kribs S, Ball I, Kearley C, LeBlanc J, Owattanapanich N, Getrajdman J, Matsushima K, Lam L, Inaba K, Figueira S, Eagles D, Khoury L, Nemnom M-J, Moors J, Kriellaars D, Mitchell D, Watson I, Totton L, Ouelett L, Benjamin S, Vautour J, McEachern S, Watson I, Ouelett L, Ringuette J, Chisholm A, Pishe T, McLaren C, Evans C, Notario L, Pannell D, Thomas-Boaz W, Freedman C, Tien H, Nathens A, Da Luz L, Li C, Vogt K, Allen L, Yoshy C, Mujoomdar A, Wiseman D, Mao R, Liu EY, Lan L, Amir T, Yan J, Singh K, Allard-Coutu A, Hameed M, Garraway N, Joos E, Isac G, Kanji H, Finlayson G, Tansley G, Lee A, Gonthier C, Belcaïd A, Moore L, Duranceau M-F, Truchon C, Berube M, Moore L, Lauzier F, Vogt K, Berry G, Tremblay L, Martel M, Pagé G, Belzile É, Pinard A-M, Evans D, Perreault K, Sirois C, Grzelak S, Turgeon A, Talbot M, Kennedy C, Hilsden R, Slobogean G, Lamb T, Lampron J, Matar M, Fernando S, Perry J, Vaillancourt C, Nathens J, Strauss R, Tillmann B, Phillips A, Haas B, Hage B, Yanchar N, Joos E, Brisson A, McKay J, Bryan F, Evans T, Qureshi A, Saadat G, Khalifa A, Bokhari F, Kaminsky M, Guiab K, Khalifa A, Bokhari F, Aly A, Evans T, Roberts A, Khalifa A, Kaminsky M, Bokhari F, Evans T, Zahid J, Roberts A, Saadat G, Messer T, Bokhari F, Keen R, Hoogers K, Widder S, Notario L, Javidan A, Johnston M, Thomas-Boaz W, Freedman C, Pannell D, Tien H, Nathens A, Da Luz L, Morch K, Scott L, Lam N, Widder S, Parekh A, Parry N, Tomlinson C, Donley N, McKee J, Wachs J, Kay M, Holland S 2021 Can J Surg View Health care providers Basic research
Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic Wendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P, Lee C-K, Arora S, Patidar GK, Khillan K, Smid WM, Vrielink H, Oreh A, Al-Riyami AZ, Hindawi S, Vermeulen M, Louw V, Burnouf T, Bloch EM, Goel R, Townsend M, So-Osman C 2021 Vox Sang View Blood operators New or improved product or process
Chapter 11: Massive hemorrhage and emergency transfusion Trudeau J, Dawe P, Shih A 2021 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Current challenges of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed C, Steele W, Davidson K, Custer B, O’Brien S, Assessment ObotSR, Policy sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2021 medRxiv View Researchers Basic research
International Forum on Walking Blood Bank Programmes: Summary Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Sekaran Nadarajan V, Dunbar N 2021 Vox Sang View Blood operators Benchmarking and standard setting
CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM 2021 J Thromb Haemost View Researchers Basic research
Rethinking platelet transfusion practices Devine DV 2021 Blood View Health care providers New or improved product or process
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): Study protocol for an international, multicenter, randomized open-label trial Bégin P, Callum J, Heddle N, Cook R, Zeller MP, Tinmouth A, Fergusson D, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitaille N, Bazin R, Shehata N, Finzi A, McGeer A, Scales D, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Jamula E, Carruthers J, Duncan J, Lucier K, Armali C, Kron A, Modi D, Auclair M-C, Avram M, Arnold DM 2021 Trials View Researchers Clinical research
Convalescent plasma for hospitalized patients with COVID-19 and the effect of plasma antibodies: a randomized controlled, open-label trial Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A, Arnold DM, for The CONCOR-1 Study Group 2021 medRxiv View Health care providers Clinical research