Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Effect of short-term vs. long-term blood storage on mortality after transfusion Heddle NM, Cook RJ, Arnold DM, Liu Y, Barty R, Crowther MA, Devereaux P, Hirsh J, Warkentin TE, Webert KE 2016 N Engl J Med View Health care providers Clinical research
Mouse Models for Immune-Mediated Platelet Destruction or Immune Thrombocytopenia (ITP) Neschadim A, Branch DR 2016 Curr Protoc Immunol View Researchers Basic research
The Ottawa criteria for the appropriate use of perioperative blood transfusions in liver resection using the RAND/UCLA appropriateness method. Bennett S, Fergusson D, Tinmouth A, McIsaac D, Pawlik T, Hebert P, Mcintyre L, Karanicolas P, Barkun J, Turgeon-Fournier A 2016 Can J Surg View Health care providers Clinical research
ResearchUnit: Data mining: digging for deeper understanding of blood components and transfusion outcomes Heddle NM, Acker JP 2016 Blood.ca website View Other Other
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections AABB Clinical Transfusion Medicine Committee, Heddle NM, Boeckh M, Grossman B, Jacobson J, Kleinman S, Tobian AAR, Webert K, Wong ECC, Roback JD 2016 Transfusion View Blood operators Clinical research
Best practices in the differential diagnosis and reporting of acute transfusion reactions Heddle N, Hillis C, Shih A 2016 Internat J Clin Transfus Med View Health care providers Clinical research
Fetal and neonatal alloimmune thrombocytopenia Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H 2016 Semin Fetal Neonatal Med View Researchers Basic research
Immune Globulin Products Nahirniak S, Lazarus A 2016 Clinical Guide to Transfusion View Health care providers Other
Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease Solh Z, Taccone MS, Marin S, Athale U, Breakey VR 2016 Pediatr Blood Cancer View Health care providers Clinical research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Anaheim 2015 Flegel WA, Castilho L, Heaton WA, Keller MA, Klapper EB, Lane WJ, Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Wagner FF, Waxman DA, Denomme GA 2016 Transfusion View Health care providers Clinical research
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
ResearchUnit: United we stand, divided we fall: using monoclonal antibody combinations to improve drug effectiveness Lazarus A 2016 Blood.ca website View Other Other
Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C Sheffield WP, Bhakta V, Yi Q-L, Jenkins C 2016 J Blood Transfus View Researchers Basic research
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC 2016 Cochrane Database Syst Rev View Health care providers Clinical research
Validation of administrative database codes for acute kidney injury in kidney transplant recipients Molnar AO, van Walraven C, McArthur E, Fergusson D, Garg AX, Knoll G 2016 Can J Kidney Health Dis View Regulators New or improved product or process
Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis Shehata N, Forster AJ, Lawrence N, Ducharme R, Fergusson DA, Chassé M, Rothwell DM, Hébert PC, Tinmouth AT, Wilson K 2015 PLoS One View Health care providers Clinical research
Age of transfused blood in critically ill adults Lacroix J, Hebert PC, Fergusson DA, Tinmouth A, Cook DJ, Marshall JC, Clayton L, McIntyre L, Callum J, Turgeon AF, Blajchman MA, Walsh TS, Stanworth SJ, Campbell H, Capellier G, Tiberghien P, Bardiaux L, van de Watering L, van der Meer NJ, Sabri E, Vo D 2015 N Engl J Med View Health care providers Clinical research
Back to Anatomy: Improving Landmarking Accuracy of Clinical Procedures Using a Novel Approach to Procedural Teaching Zeller M, Cristancho S, Mangel J, Goldszmidt M 2015 South Med J View Health care providers Other
Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? Gierczak RF, Bhakta V, Xie M, Sheffield WP 2015 J Biotechnol View Researchers Basic research
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JCM, Ni H, Ariens RAS, Wolberg AS 2015 Blood View Researchers Basic research
Gestational hypertension and preeclampsia in living kidney donors Garg AX, Nevis IF, McArthur E, Sontrop JM, Koval JJ, Lam NN, Hildebrand AM, Reese PP, Storsley L, Gill JS, Segev DL, Habbous S, Bugeja A, Knoll GA, Dipchand C, Monroy-Cuadros M, Lentine KL 2015 N Engl J Med View Health care providers Clinical research
Mouse Models of Autoimmune Diseases: Immune Thrombocytopenia Neschadim A, Branch DR 2015 Current Pharmaceutical Design View Researchers Basic research
Pitfalls in the diagnosis of heparin-induced thrombocytopenia: A 6-year experience from a reference laboratory Nazi I, Arnold DM, Moore JC, Smith JW, Ivetic N, Horsewood P, Warkentin TE, Kelton JG 2015 Am J Hematol View Health care providers Clinical research
The effect of processing method on the in vitro characteristics of red blood cell products Hansen AL, Kurach JDR, Turner TR, Jenkins C, Busch MP, Norris PJ, Dugger J, Tomasulo PA, Devine DV, Acker JP 2015 Vox Sang View Researchers Basic research
Thromboembolic events, recurrent bleeding and mortality after resuming anticoagulant following gastrointestinal bleeding. A meta-analysis Chai-Adisaksopha C, Hillis C, Monreal M, Witt DM, Crowther M 2015 Thromb Haemost View Health care providers Clinical research
BEST-TEST2: assessment of hematology trainee knowledge of transfusion medicine Lin Y, Tinmouth A, Mallick R, Haspel RL, for the BEST-TEST2 Investigators 2015 Transfusion View Other Other
Iron depletion and routine ferritin measurement in blood donors Goldman M 2015 ISBT Sci Ser View Blood operators New or improved product or process
Making good policy decisions: a discipline we cannot afford to ignore Leach Bennett J 2015 Transfusion View Blood operators Other
Quality Control of Automated Cell Counters Cembrowski GS, Clarke G 2015 Clin Lab Med View Health care providers Other
The epidemiology of imported malaria and transfusion policy in five non-endemic countries O'Brien SF, Delage G, Seed CR, Pillonel J, Fabra CC, Davison K, Kitchen A, Steele WR, Leiby DA 2015 Transfus Med Rev View Blood operators Other
Transfusion management of patients receiving daratumumab therapy for advanced plasma cell myeloma Hannon JL, Clarke G 2015 Transfusion View Health care providers Clinical research
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J View Researchers New or improved product or process
Acute Lung Injury Causes Asynchronous Alveolar Ventilation That Can Be Corrected by Individual Sighs Tabuchi A, Nickles HT, Kim M, Semple JW, Koch E, Brochard L, Slutsky AS, Pries AR, Kuebler WM 2015 Am J Respir Crit Care Med View Health care providers Clinical research
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD 2015 Am J Hematol View Researchers Basic research
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Philadelphia 2014 Flegel WA, De Castilho SL, Keller MA, Klapper EB, Moulds JM, Noizat-Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Waxman DA, Weinstock C, Wendel S, Denomme GA 2015 Blood Transfus View Health care providers Other
Perioperative Management of Dabigatran: A Prospective Cohort Study Schulman S, Carrier M, Lee AY, Shivakumar S, Blostein M, Spencer FA, Solymoss S, Barty R, Wang G, Heddle N, Douketis JD 2015 Circulation View Health care providers Clinical research
ResearchUnit: Bath time for blood cells: improving the red blood cell washing process Acker JP 2015 Blood.ca website View Other Other
ResearchUnit: Using Immunocamouflage to Fool the Immune System Scott MD 2015 Blood.ca website View Other Other
Validation of sterility testing of cord blood: Challenges and results Ramirez-Arcos S, Kou Y, Yang L, Perkins H, Taha M, Halpenny M, Elmoazzen H 2015 Transfusion View Blood operators New or improved product or process
A benchmarking program to reduce red blood cell outdating: implementation, evaluation, and a conceptual framework Barty RL, Gagliardi K, Owens W, Lauzon D, Scheuermann S, Liu Y, Wang G, Pai M, Heddle NM 2015 Transfusion View Health care providers Benchmarking and standard setting
Aggregates in platelet concentrates van der Meer PF, Dumont LJ, Lozano M, Bondar N, Wong J, Ismay S, Pink J, Nussbaumer W, Coene J, Feys HB, Compernolle V, Devine DV, Howe D, Lin CK, Sun J, Ringwald J, Strasser EF, Eckstein R, Seltsam A, Perseghin P, Proserpio P, Wakamoto S, Akino M, Takamoto S, Tadokoro K, Teo D, Shu PH, Chua SS, Jimenez-Marco T, Lozano M, Cid J, Castro E, Munoz I, Gulliksson H, Sandgren P, Thomas S, Petrik J, McColl K, Kamel H, Dugger J, Sweeney JD, Gorlin JB, Sutor LJ, Heath D, Sayers MH 2015 Vox Sang View Blood operators Benchmarking and standard setting
Anti-A and anti-B: what are they and where do they come from? Branch DR 2015 Transfusion View Researchers Other
Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide Roy R, Vidal S, Briard JG, Shiao TC, Ben RN 2015 Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 View Researchers Basic research
Dissociation of SERPINE1 mRNA from the translational repressor proteins Ago2 and TIA-1 upon platelet activation Corduan A, Ple H, Laffont B, Wallon T, Plante I, Landry P, Provost P 2015 Thromb Haemost View Researchers Basic research
Intravenous Immunoglobulin (IVIg) Utilization in Immune Thrombocytopenia (ITP): A Multi-Center, Retrospective Review Hsia C, Liu Y, Eckert K, Monga N, Elia-Pacitti J, Heddle NM 2015 Drugs Real World Outcomes View Health care providers Clinical research