Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia Aslam R, Kapur R, Segel GB, Guo L, Zufferey A, Ni H, Semple JW 2016 Exp Hematol View Researchers Basic research
Transfusion premedication practices among pediatric health care practitioners in Canada: results of a national survey Solh Z, Chan AK, Heddle NM 2016 Transfusion View Health care providers Clinical research
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature Dyba J, Tinmouth A, Bredeson C, Matthews J, Allan DS 2016 Transfus Med View Researchers Clinical research
Fibronectin maintains the balance between hemostasis and thrombosis Wang Y, Ni H 2016 Cell Mol Life Sci View Researchers Basic research
Management of immune-mediated thrombocytopenia Arnold DM, Nazi I, Smith JW, Warkentin TE 2016 Rossi's Principles of Transfusion Medicine View Health care providers Clinical research
Pathogen Inactivation Technologies: The Advent of Pathogen-Reduced Blood Components to Reduce Blood Safety Risk Devine DV, Schubert P 2016 Hematol Oncol Clin North Am View Blood operators Other
Small molecule phagocytosis inhibitors for immune cytopenias Neschadim A, Kotra LP, Branch DR 2016 Autoimmun Rev View Researchers Basic research
Association of blood donor age and sex with recipient survival after red blood cell transfusion Chassé M, Tinmouth A, English SW, Acker JP, Wilson K, Knoll G, Shehata N, Van Walraven C, Forster A, Ramsay T, McIntyre L, Fergusson DA 2016 JAMA Intern Med View Health care providers Clinical research
c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry McCarthy SDS, Sakac D, Neschadim A, Branch DR 2016 AIDS View Researchers Basic research
Exposure to ABO-nonidentical blood associated with increased in-hospital mortality in patients with group A blood Pai M, Cook R, Barty R, Eikelboom J, Lee KA, Heddle N 2016 Transfusion View Health care providers Clinical research
Laboratory management of perinatal patients with apparently "new" anti-D Hannon J, Clarke G 2016 Immunohematology View Researchers Basic research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
Molecular immunohematology at Canadian Blood Services: red cell antigen genotyping Goldman M, Hannaford K, Hannon J, Berardi P 2016 Blood.ca website View Health care providers Other
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN 2016 ACS Omega View Researchers Basic research
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A 2016 BMJ Open View Researchers Clinical research
Routine nucleic acid testing of blood donations fails to detect all human immunodeficiency virus–positive blood donors Fearon M, Scalia V, Lane D, Bigham M, Hawes G, O'Brien S, Kadkhoda K 2016 Transfusion View Health care providers Clinical research
Value of MMA crossmatch? Tong TN, Cserti-Gazdewich CM, Branch DR 2016 Transfus Med View Researchers Basic research
Reducing the age of transfused red blood cells in hospitals: ordering and allocation policies Sarhangian V, Abouee-Mehrizi H, Baron O, Berman O, Heddle NM, Barty R 2016 Vox Sang View Health care providers Benchmarking and standard setting
Riboflavin and ultraviolet illumination affects selected platelet mRNA transcript amounts differently Klein-Bosgoed C, Schubert P, Devine DV 2016 Transfusion View Researchers Basic research
Compatibility of Lactated Ringer's Solution human blood products containing red blood cells: a systematic review protocol Wolfe D, English S, Fergusson D, Kanji S, Lalu M, Mendis N, Tinmouth A, McIntyre L 2016 OHRI Publications View Researchers Clinical research
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M 2016 Diabetes View Researchers Basic research
Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock McIntyre L, Rowe BH, Walsh TS, Gray A, Arabi Y, Perner A, Gordon A, Marshall J, Cook D, Fox-Robichaud A, Bagshaw SM, Green R, Schweitzer I, Turgeon A, Zarychanski R, English S, Chassé M, Stiell I, Fergusson D 2016 BMJ Open View Health care providers Clinical research
Outbreak of acute hepatitis B virus infection associated with exposure to acupuncture Rempel S, Murti M, Buxton J, Stephens W, Watterson M, Andonov A, Fung C, Ramler G, Bigham M, Lem M 2016 Canada Communicable Disease Report View Health care providers Clinical research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Quantification of Cell-Free DNA in Red Blood Cell Units in Different Whole Blood Processing Methods Shih AW, Bhagirath VC, Heddle NM, Acker JP, Liu Y, Eikelboom JW, Liaw PC 2016 J Blood Transfus View Blood operators Basic research
ResearchUnit: Searching for safer red blood cell bags for pediatric recipients Serrano K, Acker J 2016 Blood.ca website View Other Other
Determining recruiting strategies for an adult stem cell registry Blake JT, McTaggart K, Killeen D 2016 Oper Res Health Care View Blood operators New or improved product or process
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O'Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS 2016 Lancet View Researchers Clinical research
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN 2016 ACS Omega View Researchers Basic research
Subarachnoid hemorrhage admissions retrospectively identified using a prediction model English SW, McIntyre L, Fergusson D, Turgeon A, dos Santos MP, Lum C, Chassé M, Sinclair J, Forster A, van Walraven C 2016 Neurology View Health care providers Clinical research
The mechanism and modulation of complement activation on polymer grafted cells Leung VL, Kizhakkedathu JN 2016 Acta Biomater View Researchers Basic research
Development of standard definitions for surveillance of complications related to blood donation Goldman M, Land K, Robillard P, Wiersum-Osselton J 2016 Vox Sang View Blood operators Benchmarking and standard setting
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion View Researchers Other
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev View Researchers Clinical research
ResearchUnit: Data mining 2: digging for deeper understanding of donors and transfusion outcome Fergusson DA, Acker J 2016 Blood.ca website View Other Other
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL 2016 BMJ Open View Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife View Researchers Clinical research
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials View Researchers Basic research
Transfusion reactions: prevention, diagnosis, and treatment Delaney M, Wendel S, Bercovitz RS, Cid J, Cohn C, Dunbar NM, Apelseth TO, Popovsky M, Stanworth SJ, Tinmouth A, Van De Watering L, Waters JH, Yazer M, Ziman A 2016 Lancet View Health care providers Clinical research
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases Webert K, Kelton J 2016 Aspirin and related drugs View Health care providers Clinical research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale View Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
Using simulation for strategic blood supply chain design in the Canadian prairies Blake J, McTaggart K 2016 Proceedings of the 6th International Conference on SIMULTECH View Blood operators New or improved product or process
Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study Heddle NM, Arnold DM, Acker JP, Liu Y, Barty RL, Eikelboom JW, Webert KE, Hsia CC, O'Brien SF, Cook RJ 2016 Lancet Haematol View Researchers Clinical research
Transfusion-transmitted malaria: is hope around the corner? O'Brien SF 2016 Lancet View Researchers Other
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
ResearchUnit: Data mining: digging for deeper understanding of blood components and transfusion outcomes Heddle NM, Acker JP 2016 Blood.ca website View Other Other