Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Quality of evidence-based guidelines for platelet transfusion and use: A systematic review Al-Riyami AZ, Jug R, La Rocca U, Keshavarz H, Landry D, Shehata N, Stanworth SJ, Nahirniak S 2021 Transfusion View Researchers Benchmarking and standard setting
Themed issue – focusing on donor assessment, motivation and vigilance O’Brien SF, Ullum H, Seed CR 2021 Vox Sang View Researchers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
Challenging the 30-min rule for thawed plasma Ramirez-Arcos S, Howell A, Bearne J, Bhakta V, Bower L, Cardigan R, Girard M, Kou Y, McDonald C, Nolin M-È, Sawicka D, Sheffield W 2021 Vox Sang View Researchers Benchmarking and standard setting
How do I think about blood donor eligibility criteria for medical conditions? Goldman M 2021 Transfusion View Researchers Benchmarking and standard setting
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 medRxiv View Researchers New or improved product or process
ResearchUnit: A proposed mechanism for vaccine-induced thrombotic thrombocytopenia Batarfi K 2021 Blood.ca website View Researchers Clinical research
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP 2022 Transfus Med Hemother View Researchers Clinical research
A thermoreversible poly(choline phosphate) based universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Macromol Biosci View Researchers Basic research
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice Liu J, Santhanakrishnan M, Natarajan P, Gibb DR, Eisenbarth SC, Tormey CA, Siddon AJ, Stowell SR, Branch DR, Hendrickson JE 2016 Blood View Researchers Basic research
Bacterial survival and distribution during buffy coat platelet production Taha M, Kalab M, Yi QL, Maurer E, Jenkins C, Schubert P, Ramirez-Arcos S 2016 Vox Sang View Researchers New or improved product or process
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med View Researchers Clinical research
Concentré de recherche: La présence de résidus de plasma favorise l'adhérence des bactéries à la paroi des poches utilisées pour les concentrés de plaquettes Ramirez-Arcos S 2017 Blood.ca website View Researchers Basic research
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence Kayibanda JF, Hiremath S, Knoll GA, Fergusson D, Chow BJ, Shabana W, Akbari A 2014 Syst Rev View Researchers Clinical research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
In silico analysis suggests interaction between Ebola virus and the extracellular matrix Veljkovic V, Glisic S, Muller CP, Scotch M, Branch DR, Perovic VR, Sencanski M, Veljkovic N, Colombatti A 2015 Front Microbiol View Researchers Basic research
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
Microscope-based label-free microfluidic cytometry Su X, Kirkwood SE, Gupta M, Marquez-Curtis L, Qiu Y, Janowska-Wieczorek A, Rozmus W, Tsui YY 2011 Opt Express View Researchers New or improved product or process
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Quality and Safety of Blood Products Ramirez-Arcos S, Marks DC, Acker JP, Sheffield WP 2016 J Blood Transfus View Researchers Other
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, McIsaac DI, Hébert PC, Karanicolas PJ, McIntyre L, Turgeon AF, Barkun J, Fergusson D 2017 HPB View Researchers Clinical research
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T 2014 Am J Blood Res View Researchers Basic research
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth View Researchers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group 2021 Vox Sang View Researchers Clinical research
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A 2020 medRxiv View Researchers Clinical research
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes Brydon M, Kephart G, Payne JI, Blake J 2020 J Med Imaging Radiat Sci View Researchers New or improved product or process
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM 2022 Transfusion View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP 2022 Blood Adv View Researchers Clinical research
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS 2023 Transplantation View Researchers Basic research
A Survey of Patient Experience in CML: American and Canadian Perspectives Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E 2023 Patient Prefer Adherence View Researchers Clinical research
Database-driven research and big data analytic approaches in transfusion medicine Ning S, Li N, Barty R, Arnold D, Heddle NM 2022 Transfusion View Researchers Clinical research
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP 2022 Vox Sang View Researchers Clinical research
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges Wolfe A 2022 Blood.ca website View Researchers Benchmarking and standard setting
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H 2017 Nat Commun View Researchers Basic research
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data Jordan A, Chen D, Yi QL, Kanias T, Gladwin MT, Acker JP 2016 Vox Sang View Researchers Basic research
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One View Researchers Basic research
C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury Kapur R, Kim M, Shanmugabhavananthan S, Liu J, Li Y, Semple JW 2015 Blood View Researchers Basic research
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units Pasha R, Elmoazzen H, Pineault N 2017 Transfusion View Researchers New or improved product or process
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry View Researchers Basic research
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF 2015 J Org Chem View Researchers Basic research
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost View Researchers Basic research
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH 2017 Blood View Researchers Basic research
In-Gel Technology for PCR Genotyping and Pathogen Detection Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP 2010 Anal Chem View Researchers New or improved product or process