Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Sort descending Project Start Date Project End Date Total $ Awarded
TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) Principal Investigator: CSERTI-GAZDEWICH, Christine

Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert
Intramural Research Grant Program 278027.5
Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: FREED, Darren
Intramural Research Grant Program 121834.0
Fc receptor blockade in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery
Intramural Research Grant Program 400000.0
Development of a small molecule cocktail for the expansion of cord blood stem cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie
Intramural Research Grant Program 237600.0
PREMISE: Point-of-care hemoglobin accuracy and transfusion outcomes in non-cardiac surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, MCISAAC, Daniel, SHAW, Julie, RAMSAY, Tim, PRESSEAU, Justin, WHERRETT, Christopher, CARRIER, François-Martin, SEELY, Andrew, BRYSON, Gregory
Intramural Research Grant Program 392974.0
Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu
Intramural Research Grant Program 400000.0
Small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi P.
Intramural Research Grant Program 399130.0
Plasma transfusion or plasma protein product infusion in a murine model of trauma Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: PRYZDIAL, Edward
Intramural Research Grant Program 257414.8
Anti-RBC monoclonal antibodies as a replacement for IVIg and anti-D in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: BRANCH, Donald, DUNN, Shannon
Intramural Research Grant Program 400000.0
Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo
Intramural Research Grant Program 250660.0
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Small molecule drug development of phagocytosis inhibitors Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P.
Intramural Research Grant Program 428468.4
Translating novel clotting factor X function to treat thrombosis Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William
Intramural Research Grant Program 369052.0
Of skin, sperm, and blood: A comparative analysis of exemptions in Canadian human tissue legislation Principal Investigator: CATTAPAN, Alana

Co-Investigator(s) / Trainee: VON TIGERSTROM, Barbara, NELSON, Eric, DAWSON, Rosanne
James Kreppner Award Program 43275.0
The role of stakeholder trust in OTDT policy change: public and professional attitudes to ante-mortem interventions in organ donation Principal Investigator: CHANDLER, Jennifer

Co-Investigator(s) / Trainee: McKAY, Lindsey
James Kreppner Award Program 50000.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program 50000.0
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake, MARCON, Alessandro
James Kreppner Award Program 50000.0
Legal and policy strategies to optimize organ donation in Alberta Principal Investigator: TOEWS, Maeghan

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program 150000.0
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator: GRUBEN, Vanessa

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program 150000.0
Evaluating transfusion medicine patterns of practice across GEMINI sites Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse
Kenneth J. Fyke Award Program 98822.0
Prospective observational study of organ deceased donor management in 3 ICUs - a pilot study (the DONATE pilot study) Principal Investigator: MEADE, Maureen

Co-Investigator(s) / Trainee: D'ARAGON, Frederick, RIBIC, Christine, SHARPE, Michael, BALL, Ian, WILLIAMSON, David, DHANANI, Sonny, HANNA, Steven
Kenneth J. Fyke Award Program 89555.1
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program 100000.0
Canadians’ attitudes and opinions regarding cardiac donation after cardiocirculatory death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt, D'ARAGON, Fred, PARSONS LEIGH, Jenna, HONARMAND, Kimia, BASMAJI, John, SIBBALD, Robert
Kenneth J. Fyke Award Program 95929.0
The pan-Canadian immunoglobulin database: Enabling utilization reporting and personalized treatment using data mining techniques for immunoglobulin Principal Investigator: LI, Na

Co-Investigator(s) / Trainee: DOWN, Douglas, CHIANG, Fei, LEE, Joon, HEDDLE, Nancy, ARNOLD, Donald, CALLUM, Jeannie, SIDHU, Davinder, BARTY, Rebecca
Kenneth J. Fyke Award Program 100000.0
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program 129400.0
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program 200500.0
Assessing the acceptability and feasibility of a plasma donation program for gbMSM in Montréal from the point of view of cis and trans gbMSM, volunteers from Héma-Québec, current donors, and plasma product recipients Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, HAW, Jennie, MONTEITH, Kenneth, MYHAL, Geneviève, PRESSEAU, Justin, PIRNAT, Bojan, LAPIERRE, Don
MSM Plasma Program 390970.0
The Calgary Plasma Study: feasibility of implementing source plasma donation with alternative screening eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, FOSTER, Terrie, VESNAVER, Elisabeth, GERMAIN, Marc, ROSSER, Andrew, LAPIERRE, Don, HILL, Nolan
MSM Plasma Program 399875.0
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program 410000.0
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell, SKAKOON-SPARLING, Shayna
MSM Research Grant Program 452500.0
Sex Now 2018: A national survey on blood donation and undiagnosed blood borne infections Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: TRUSSLER, Terry, GILBERT, Mark, SALWAY, Travis, JOLLIMORE, Jody, HAM, David, LOFTUS, Patrick, OLIVER, Brent, HANSEN, Brian, VISSER, Floyd, BRENNAN, David, GRACE, Daniel, OTIS, Joanne, LEBOUCHÉ, Bertrand, NUMER, Matthew, SAXTON, Peter
MSM Research Grant Program 421719.0
Operational impact of individual risk assessment options Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: ROBILLARD, Pierre, GOLDMAN, Mindy, MYHAL, Geneviève
MSM Research Grant Program 168000.0
Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel
MSM Research Grant Program 229507.0
Assessing alternative Canadian Blood Services blood donor deferral screening policies for men who have sex with men Principal Investigator: BRENNAN, David

Co-Investigator(s) / Trainee: ADAM, Barry, HART, Trevor, LACHOWSKY, Nathan, GRACE, Daniel
MSM Research Grant Program 60000.0
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program 39618.0
Safety, Acceptance, Fairness & Equality (SAFE project): Acceptable risk and donor selection Principal Investigator: DITTO, Blaine

Co-Investigator(s) / Trainee: FERGUSON, Eamonn
MSM Research Grant Program 49412.5
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 24000.0
Assessing unintentional creation of bias against MSM as a function of exposure to blood donor screening questionnaire and assessing sexual behaviour risk factors of those successfully passing blood donor screening Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee:
MSM Research Grant Program 56000.0
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program 309940.0
Attitudes, behaviours, and acceptability related to current and future blood donation policy: A qualitative study of gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montréal Principal Investigator: GRACE, Daniel

Co-Investigator(s) / Trainee: HART, Trevor, LAMBERT, Gilles, COX, Joseph , ADAM, Barry , BRENNAN, David , LACHOWSKY, Nathan, MOORE, David
MSM Research Grant Program 60000.0
Understanding general population impact and opportunities from changes to blood donation deferral screening and criteria for men who have sex with men Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: BRENNAN, David, CARD, Kiffer, DRYDEN, OmiSoore, GASPAR, Mark, GILBERT, Mark, GRACE, Daniel, KNIGHT, Rodney, LEBOUCHÉ, Bertrand, MORGAN, Jeffrey, SALWAY, Travis
MSM Research Grant Program 310000.0
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program 50000.0
Mathematical modeling - comparing HIV risk between MSM donation strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 18000.0
Mechanism of anti-D-like antibody-mediated amelioration of immune thrombocytopenia (ITP) Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: YU, Xiaojie (Ben)
Postdoctoral Fellowship Program 106200.0
Reducing IVIG usage by developing novel prophylaxis therapies against FNAIT Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: PASMAN, Yfke
Postdoctoral Fellowship Program 165000.0
Transfusion options in coagulopathy: Efficacy in controlling bleeding Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: QADRI, Syed
Postdoctoral Fellowship Program 151800.0
New platform for targeted gene editing of hematopoietic stem cells for cellular
therapy
Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MAGANTI, Harinad
Postdoctoral Fellowship Program 120000.0
Understanding IVIg mechanism(s) of action in alleviating immune platelet destruction and thrombocytopenia Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee: KAPUR, Ricky
Postdoctoral Fellowship Program 106200.0
Identification of mechanisms leading to antibody independent RBC hemolysis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: FRIAS BOLIGAN, Kayluz
Postdoctoral Fellowship Program 150000.0