Our Funded Research Projects

Updated September 2023

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort descending Total $ Awarded
Release, delivery and cell programming effects of platelet microparticles and microRNAs Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: BOILARD, Eric
Canadian Blood Services-CIHR Partnership Operating Grant Program $427,422.00
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program $320,504.00
Studying and alleviating the effects of platelet microparticles induced by pathogen reduction of platelet concentrates Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: LAUGIER, Jonathan
Graduate Fellowship Program $52,000.00
The Canadian National Transplant Research Program: increasing donating and improving transplantation outcomes Principal Investigator: WEST, Lori

Co-Investigator(s) / Trainee:
Transplantation Research Program $250,000.00
Polyhemoglobin catalase superoxide dismutase carbonic anhydrase: a novel soluble biotherapeutic with no cardiac toxicity for hemorrhagic shock and other uses Principal Investigator: CHANG, Thomas

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program $224,520.00
An innovative digital strategy for dissemination of Choosing Wisely Canada guidelines in transfusion medicine Principal Investigator: CAMPBELL, Clinton

Co-Investigator(s) / Trainee: LABRECQUE, Suzanne, LABELLE, Peter, AL-JEDANI, Hanadi, SADEK, Irene, KAHWASH, Eiad
BloodTechNet Award Program $25,000.00
PID (Primary Immune Deficiency) Toolkit App Principal Investigator: DARNEL, Susanna

Co-Investigator(s) / Trainee: LI, Cecilia, BEAUCHAMP, Aimee, MORRISON, Doug, DALLAS, Karen, MICHAAN, Jack, TAVASZI, Alina, DENESIN, Pam, FUNG, Rene, British Columbia Primary Immune Deficiency (PID) Group Members
BloodTechNet Award Program $25,000.00
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator: ENGLISH, Shane

Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program $157,172.00
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program $317,469.00
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee: KUEBLER, Wolfgang M.
Canadian Blood Services-CIHR Partnership Operating Grant Program $398,982.00
Myocardial Ischemia and Transfusion. The MINT rollover trial Principal Investigator: HEBERT, Paul

Co-Investigator(s) / Trainee: CARSON, Jeffrey L., DEVEREAUX, Philip J., EIKELBOOM, John W., FERGUSSON, Dean A., GOODMAN, Shaun G. , MCALISTER, Finlay A. , TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program $140,210.00
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program $100,000.00
DNA aptamers for detection of red blood cells destined for rapid post-transfusion clearance Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: DONKOR, David
Postdoctoral Fellowship Program $150,000.00
Improving pathogen inactivation: the dengue virus-induced platelet proteome Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu
Graduate Fellowship Program $104,000.00
Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease Principal Investigator: TRUDEL, Marie

Co-Investigator(s) / Trainee: MOROY, Tarik
Canadian Blood Services-CIHR Partnership Operating Grant Program $453,132.00
Microfluidic devices to measure the deformability of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: SCOTT, Mark D.
Canadian Blood Services-CIHR Partnership Operating Grant Program $398,301.00
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) Principal Investigator: KUEBLER, Wolfgang

Co-Investigator(s) / Trainee: SEMPLE, John W.
Canadian Blood Services-CIHR Partnership Operating Grant Program $328,712.00
Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu
Intramural Research Grant Program $400,000.00
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator: GRUBEN, Vanessa

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program $150,000.00
Social media for knowledge translation and education 3 (SoMe-KTE3): Transfusion, thrombosis, and hemostasis Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: CHAN, Teresa, DE WIT, Kristin, BHAGIRATH, Vinai, YEH, Calvin, CASTELLUCI, Lana, ELAHIE, Allahna, HEDDLE, Nancy, THOMA, Brent
BloodTechNet Award Program $30,000.00
Podcast for FNAIT and ICTMG red cell specifications for hemoglobinopathies guidelines Principal Investigator: SHEHATA, Nadine

Co-Investigator(s) / Trainee:
BloodTechNet Award Program $6,200.00
Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: XU, Miao
Graduate Fellowship Program $52,000.00
Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo
Intramural Research Grant Program $250,660.00
Mathematical modeling - comparing HIV risk between MSM donation strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program $18,000.00
Feasibility in Canada for a non-invasive prenatal testing using single-exon fetal RHD determination Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: CLARKE, Gwen, BHATTI, Aniqa
Blood Efficiency Accelerator Program $20,000.00
Impact of storage on the function of cord blood hematopoietic stem and progenitor cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: JAHAN, Suria
Graduate Fellowship Program $104,000.00
Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: POISSON, Jessica
Graduate Fellowship Program $82,000.00
Better blood transfusion - Phase two Principal Investigator: O'REILLY, Clare

Co-Investigator(s) / Trainee: PARKE, Graham, MORRISON, Douglas, CHIPPERFIELD, Kate, EVELEIGH, Shari, WILSON, Sophie
BloodTechNet Award Program $5,250.00
Stem Cell Transplantation Multimedia Toolkit Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: ALLAN, David, MESSNER, Hans, PETRASZKO, Tanya, ZUCCHET, Alyssa, DONNELLY, Sarah, HAMM, Taylor, THATCHER, Alicia, LADD, Aedan, CHAN, Sam, SUPPIAH, Roopa, WINQUIST, Lauren, LAU, Janny, PIETROBAN, Adam, LONDON, Sydney, COLES, Jenna
BloodTechNet Award Program $2,000.00
Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: CHASSE, Michael, FERGUSSON, Dean A., GOLDMAN, Mindy R., O'BRIEN, Sheila F., SPRAGUE, Ann, van WALRAVEN, Carl, WALKER, Mark C., WILSON, Kumanan
Canadian Blood Services-CIHR Partnership Operating Grant Program $135,657.00
Polymer-based manufacturing tolerogenic miRNA-based therapeutics Principal Investigator: SCOTT, Mark

Co-Investigator(s) / Trainee: HORWITZ, Marc S.
Canadian Blood Services-CIHR Partnership Operating Grant Program $491,125.00
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program $50,000.00
Process evaluation of the Canadian Blood Services' cord blood bank: managerial and donor perspectives Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: HAW, Jennie
CIHR Health System Impact Fellowship $46,500.00
Study of the mechanisms implicated in platelets microparticle internalization by blood cells Principal Investigator: BOILARD, Eric

Co-Investigator(s) / Trainee: MARCOUX, Genevieve
Graduate Fellowship Program $104,000.00
Operational impact of individual risk assessment options Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: ROBILLARD, Pierre, GOLDMAN, Mindy, MYHAL, Geneviève
MSM Research Grant Program $168,000.00
Recombinant Fc multimers to replace IVIG Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: LEWIS, Bonnie
Graduate Fellowship Program $104,000.00
National evaluation of platelet transport bags to reduce wastage Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: CALLUM, Jeannie, LIN, Yulia, LIEBERMAN, Lani, PENDERGRAST, Jacob, CSERTI-GAZDEWICH, Christine
Small Project Funding Program $9,740.00
The role of stakeholder trust in OTDT policy change: public and professional attitudes to ante-mortem interventions in organ donation Principal Investigator: CHANDLER, Jennifer

Co-Investigator(s) / Trainee: McKAY, Lindsey
James Kreppner Award Program $50,000.00
An evaluation of learner perspectives and outcomes following completion of the transfusion medicine area of focused competence Principal Investigator: TSENG, Eric Kuo

Co-Investigator(s) / Trainee: ZELLER, Michelle
Qualitative Education Funding $9,875.00
Human monoclonal CD44 antibodies as potential IVIg replacements Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $336,000.00
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $224,417.00
Assessment of the quality of granulocyte concentrates to optimise their use in transfusion therapy Principal Investigator: FERNANDES, Maria

Co-Investigator(s) / Trainee: GIRARD, Melissa, BRANCH, Donald
Blood Efficiency Accelerator Program $30,000.00
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program $332,942.00
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator: EMERIAUD, Guillaume

Co-Investigator(s) / Trainee: DU PONT-THIBIDEAU, Genevieve, FONTELA, Patricia S. , GAUVIN, France, GILFOYLE, Elaine, HUTCHISON, James S., LACROIX, Jacques, MENON, Kusum, ROBITAILLE, Nancy, TINMOUTH, Alan T., TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program $477,651.00
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program $300,000.00
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program $101,200.00
A program to minimize preventable and inappropriate blood product transfusions in liver surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: BAKER, Laura, TINMOUTH, Alan, SAIDENBERG, Elianna, WHERRETT, Christopher, WORKNEH, Aklile
Blood Efficiency Accelerator Program $20,000.00
Platelet desialylation: novel mechanism of platelet clearance and immune tolerance Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LI, June
Graduate Fellowship Program $104,000.00
A novel clot-dissolving agent derived from clotting factor Va Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: LEE, Frank
Graduate Fellowship Program $39,500.00
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program $24,000.00