Our Funded Research Projects

Updated April 2024

Title Sort descending Principal Investigator / Supervisor Program Project Start Date Project End Date Total $ Awarded
A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) Principal Investigator: BARTOSZKO, Justyna

Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly
Intramural Research Grant Program 242617.0
A Framework for Accelerated Synthesis of Trial Evidence – FAST Evidence - to assess efficacy of mesenchymal stromal cells and convalescent plasma for COVID-19 Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, LALU, Manoj
Blood Efficiency Accelerator Program 25000.0
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program 50000.0
A machine learning based framework to analyze blood product transactional data for reducing discards Principal Investigator: CHENG, Calvino

Co-Investigator(s) / Trainee: ABIDI, Syed Sibte Raza, BLAKE, John, LIWSKI, Robert, QUINN, Jason, ABUSHAREKH, Ashraf, ABIDI, Samina, XIANG, Richard
Blood Efficiency Accelerator Program 29950.0
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program 332942.0
A novel clot-dissolving agent derived from clotting factor Va Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: LEE, Frank
Graduate Fellowship Program 39500.0
A program to minimize preventable and inappropriate blood product transfusions in liver surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: BAKER, Laura, TINMOUTH, Alan, SAIDENBERG, Elianna, WHERRETT, Christopher, WORKNEH, Aklile
Blood Efficiency Accelerator Program 20000.0
A Simulation Model to Inform Best Practices for Inventory Management of Group O Negative Red Blood Cells Principal Investigator: RUTHERFORD, Alexander

Co-Investigator(s) / Trainee: BLAKE, John, SHIH, Andrew, MORRISON, Douglas, SAREMI, Alireza
Blood Efficiency Accelerator Program 29500.0
A study to understand C1 esterase inhibitor distribution and patterns of use in Canada Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: HEDDLE, Nancy, KEITH, Paul, WASERMAN, SUSAN, WEBERT, Kathryn, NING, Shuoyan, SHIH, Andrew, MORRISON, Doug, YAN, Matthew
Blood Efficiency Accelerator Program 29858.6
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program 410000.0
Addressing racial disparity in blood, stem cell, and organ and tissue donor pools Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: OKONOFUA, Sylvia, YAN, Matthew, KHANDELWAL, Aditi, PENDERGRAST, Jacob, LEEIES, Murdoch, TINGA, Biba, HAW, Jennie, JAGELAVICIUTE, Gabriela, ROSENFELD, Aaron, KHANOLKAR, Rutvij, SEGALL, Romy, BELLINI, Jonathan, MORAKINYO, Tobi, AGYEPONG, Revée
BloodTechNet Award Program 34150.0
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program 39618.0
An evaluation of learner perspectives and outcomes following completion of the transfusion medicine area of focused competence Principal Investigator: TSENG, Eric Kuo

Co-Investigator(s) / Trainee: ZELLER, Michelle
Qualitative Education Funding 9875.0
An innovative digital strategy for dissemination of Choosing Wisely Canada guidelines in transfusion medicine Principal Investigator: CAMPBELL, Clinton

Co-Investigator(s) / Trainee: LABRECQUE, Suzanne, LABELLE, Peter, AL-JEDANI, Hanadi, SADEK, Irene, KAHWASH, Eiad
BloodTechNet Award Program 25000.0
An interactive virtual tour of blood product manufacturing at Canadian Blood Services Principal Investigator: BODNAR, Melanie

Co-Investigator(s) / Trainee: CHARGÉ, Sophie, YAN, Mathew, ABE, Tricia, TORDON, Bryan, CLARKE, Gwen
BloodTechNet Award Program 20000.0
Anemia-induced bleeding in thrombocytopenic patients with blood cancer Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: MODI, Dimpy
Graduate Fellowship Program 70000.0
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator: ENGLISH, Shane

Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program 157172.0
Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: XU, Miao
Graduate Fellowship Program 52000.0
Anti-GPIb- and anti-GPIIbIIIa- mediated immune thrombocytopenia: Mechanisms and actions of intravenous IgG (IVIG) and alternative therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald
Intramural Research Grant Program 412010.3
Anti-RBC monoclonal antibodies as a replacement for IVIg and anti-D in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: BRANCH, Donald, DUNN, Shannon
Intramural Research Grant Program 400000.0
Antibodies to CD44 as a potential replacement for IVIg in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William
Intramural Research Grant Program 300000.0
Applying educational tools of knowledge translation to reduce the inappropriate use of plasma in Ontario: a collaboration between Canadian Blood Services and Ontario hospitals Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: SKEATE, Robert, BERTA, Donna, CALLUM, Jeannie, LIMA, Ana, ZELLER, Michelle, ELAHIE, Allahna, HEDDLE, Nancy, THOMPSON, Troy, TINMOUTH, Alan, SHEHATA, Nadine, ILAGAN, Cesario
BloodTechNet Award Program 7200.0
Are cervical cancer brachytherapy outcomes associated with pre-brachytherapy hemoglobin values and transfusion practice? An observational study comparing two academic centres. Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: LAZO-LANGER, Alejandro, D'SOUZA, David, CALLUM, Jeannie, LEUNG, Eric, CHIN-YEE, Ian
Blood Efficiency Accelerator Program 27669.5
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program 129400.0
Assessing alternative Canadian Blood Services blood donor deferral screening policies for men who have sex with men Principal Investigator: BRENNAN, David

Co-Investigator(s) / Trainee: ADAM, Barry, HART, Trevor, LACHOWSKY, Nathan, GRACE, Daniel
MSM Research Grant Program 60000.0
Assessing the acceptability and feasibility of a plasma donation program for gbMSM in Montréal from the point of view of cis and trans gbMSM, volunteers from Héma-Québec, current donors, and plasma product recipients Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, HAW, Jennie, MONTEITH, Kenneth, MYHAL, Geneviève, PRESSEAU, Justin, PIRNAT, Bojan, LAPIERRE, Don
MSM Plasma Program 390970.0
Assessing the impact of donor manufacturing characteristics on survival of transfused red blood cells Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: ACKER, Jason, FERGUSSON, Dean, CHASSÉ, Michaël
Intramural Research Grant Program 90935.0
Assessing the relationship between red blood cell deformability and transfusion lifetime Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: LAMOUREUX, Erik
Graduate Fellowship Program 52000.0
Assessing unintentional creation of bias against MSM as a function of exposure to blood donor screening questionnaire and assessing sexual behaviour risk factors of those successfully passing blood donor screening Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee:
MSM Research Grant Program 56000.0
Assessment of fluorinated ice crystallization inhibitors: cryopreservation of hematopoietic stem cells and red blood cells Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: BRIARD, Jennie
Graduate Fellowship Program 96000.0
Assessment of the quality of granulocyte concentrates to optimise their use in transfusion therapy Principal Investigator: FERNANDES, Maria

Co-Investigator(s) / Trainee: GIRARD, Melissa, BRANCH, Donald
Blood Efficiency Accelerator Program 30000.0
Attitudes, behaviours, and acceptability related to current and future blood donation policy: A qualitative study of gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montréal Principal Investigator: GRACE, Daniel

Co-Investigator(s) / Trainee: HART, Trevor, LAMBERT, Gilles, COX, Joseph , ADAM, Barry , BRENNAN, David , LACHOWSKY, Nathan, MOORE, David
MSM Research Grant Program 60000.0
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program 200500.0
Better blood transfusion - Phase two Principal Investigator: O'REILLY, Clare

Co-Investigator(s) / Trainee: PARKE, Graham, MORRISON, Douglas, CHIPPERFIELD, Kate, EVELEIGH, Shari, WILSON, Sophie
BloodTechNet Award Program 5250.0
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy
Intramural Research Grant Program 200000.0
Blood and stem cell donation for men who have sex with men in Canada: A toolkit for healthcare professionals Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, SHIH, Andrew, ELMOAZZEN, Heidi, ALLAN, David, PETRASZKO, Tanya, YAN, Matthew, COUPAL, Dylan, SEGALL, Romy, CHOWDHURY, Fuad, CAI, Helen, KUMAR, Shamini Vijaya, TRAADE, Daniel, ROSENFELD, Aaron, KAVEH, Farrokhi
BloodTechNet Award Program 20000.0
Blood product demand forecast modeling using clinical predictors Principal Investigator: DOWN, Douglas

Co-Investigator(s) / Trainee: BLAKE, John , TRIFUNOV, Rick, COURTNEY, Thomas, HEDDLE, Nancy, CHIANG, Fei, LI, Na
Blood Efficiency Accelerator Program 30000.0
Blood utilization epidemiological profile to evaluate appropriate use (BLUE) Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: ARNOLD, Donald, WEBERT, Kathryn, HEDDLE, Nancy, NING, Shuoyan, BARTY, Rebecca
Blood Efficiency Accelerator Program 29964.0
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake, MARCON, Alessandro
James Kreppner Award Program 50000.0
Canadians’ attitudes and opinions regarding cardiac donation after cardiocirculatory death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt, D'ARAGON, Fred, PARSONS LEIGH, Jenna, HONARMAND, Kimia, BASMAJI, John, SIBBALD, Robert
Kenneth J. Fyke Award Program 95929.0
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: LI, Wenhui
Graduate Fellowship Program 70000.0
Cellular therapy to improve CD4+ T-Cell responses in humanized mice infected with HIV-1: adoptive transfer of CD4+ T-cells lacking s-Src activity Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: McCARTHY, Stephen
Graduate Fellowship Program 96000.0
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program 320504.0
Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal Principal Investigator: HOPE, Kristin

Co-Investigator(s) / Trainee: RENTAS, Stefan
Graduate Fellowship Program 100000.0
Clot-targeting the novel thrombolytic activity of recombinant factor X Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: HAO, Lihua
Postdoctoral Fellowship Program 164200.0
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program 300000.0
Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) Principal Investigator: MACK, Johnathan

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell
Blood Efficiency Accelerator Program 26385.0
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NAZY, Ishac
Intramural Research Grant Program 274854.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0