Our Funded Research Projects
Updated September 2023
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Title | Principal Investigator / Supervisor | Program | Project Start Date Sort descending | Project End Date | Total $ Awarded |
---|---|---|---|---|---|
The use of antibody-mediated immune suppression as a model in the development of a replacement for RhD prophylaxis in haemolytic disease of the fetus and newborn | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $620,822.00 | ||
Towards the impact of protein synthesis in human platelets to transfusion medicine | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: BOSGOED, Christa |
Graduate Fellowship Program | $92,000.00 | ||
Role of skin disinfection and buffy coat platelet production on residual bacterial contamination in platelet concentrates and cord blood stem cells | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: TAHA, Mariam |
Graduate Fellowship Program | $92,000.00 | ||
Studies on the development of biocompatible antimicrobial platelet storage devices | Principal Investigator: BROOKS, Don Co-Investigator(s) / Trainee: HADJESFANDIARI, Narges |
Graduate Fellowship Program | $96,000.00 | ||
Transfusion requirements in cardiac surgery (TRICS II) | Principal Investigator: SHEHATA, Nadine Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership New Investigator Program | $300,000.00 | ||
Assessment of fluorinated ice crystallization inhibitors: cryopreservation of hematopoietic stem cells and red blood cells | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: BRIARD, Jennie |
Graduate Fellowship Program | $96,000.00 | ||
Pathogenesis of fetal and neonatal alloimmune thrombocytopenia and mechanisms of IVIG therapy | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: YOUGBARE, Issaka |
Postdoctoral Fellowship Program | $151,800.00 | ||
Identification of protein biomarkers for red cell quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: CHEN, Deborah |
Graduate Fellowship Program | $100,000.00 | ||
The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | $100,000.00 | ||
Platelet microRNAs during storage under blood bank conditions | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: HITZLER, Walter |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $349,548.00 | ||
Small molecule inhibitors of phagocytosis as replacement therapy for IVIG | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $230,000.00 | ||
Transfusion of red cells in hematopoietic stem cell transplantation: The TRIST Study | Principal Investigator: TAY, Jason Co-Investigator(s) / Trainee: ALLAN, David S. , COYLE, Douglas A. , FERGUSSON, Dean A. , TINMOUTH, Alan T. , WALKER, Irwin R |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $340,817.00 | ||
Development of novel blood vessel and organ sealants for blood conservation in surgical practice | Principal Investigator: BROOKS, Don Co-Investigator(s) / Trainee: DU, Caigan , HSIANG, York N. , KIZHAKKEDATHU, Jayachandran N. , KO, Frank K. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $240,996.00 | ||
The Canadian National Transplant Research Program: increasing donating and improving transplantation outcomes | Principal Investigator: WEST, Lori Co-Investigator(s) / Trainee: |
Transplantation Research Program | $250,000.00 | ||
Improving the cryostorage of blood products using novel small molecule cryoprotectants | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: ACKER, Jason P. , ALLAN, David S. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $384,180.00 | ||
Transfusion-related Epstein-Barr Virus (EBV) infection among allogeneic stem cell transplant pediatric recipients: A multicenter prospective cohort study (TREASuRE Study) | Principal Investigator: TROTTIER, Helen Co-Investigator(s) / Trainee: ALFIERI, Carolina , BUTEAU, Chantal , DUVAL, Michel , LACROIX, Jacques , ROBITAILLE, Nancy , SPINELLA, Philip , TUCCI, Marisa |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $519,766.00 | ||
MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | $100,000.00 | ||
Residual risk of transfusion-transmitted cytomegalovirus infection: incidence and pathogenesis | Principal Investigator: PREIKSAITIS, Jutta Co-Investigator(s) / Trainee: O'BRIEN, Sheila F., FEARON, Margaret, NAHIRNIAK, Susan |
Intramural Research Grant Program | $260,451.00 | ||
Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal | Principal Investigator: HOPE, Kristin Co-Investigator(s) / Trainee: RENTAS, Stefan |
Graduate Fellowship Program | $100,000.00 | ||
Antibodies to CD44 as a potential replacement for IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William |
Intramural Research Grant Program | $300,000.00 | ||
Polyhemoglobin catalase superoxide dismutase carbonic anhydrase: a novel soluble biotherapeutic with no cardiac toxicity for hemorrhagic shock and other uses | Principal Investigator: CHANG, Thomas Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $224,520.00 | ||
University of Ottawa Centre for Transfusion Research | Principal Investigator: TINMOUTH, Alan Co-Investigator(s) / Trainee: |
Program Support Award for Canadian Transfusion Medicine and Science Research Program | $799,887.81 | ||
Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing major liver resection: a pilot randomized controlled trial | Principal Investigator: KARANICOLAS, Paul Co-Investigator(s) / Trainee: GUYATT, Gordon H. , CHAUDHURY, Prosanto K. , DIXON, Elijah , LIN, Yulia , McCLUSKEY, Stuart A. , PORTER, Geoffrey A. , TARSHIS, Jordan , WEI, Alice C. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $248,319.00 | ||
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $320,504.00 | ||
The Centre for Blood Research | Principal Investigator: CONWAY, Ed Co-Investigator(s) / Trainee: |
Program Support Award for Canadian Transfusion Medicine and Science Research Program | $776,229.00 | ||
Understanding host mechanisms responsible for immune platelet destruction and thrombocytopenia | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $406,003.00 | ||
McMaster Transfusion Research Program | Principal Investigator: HEDDLE, Nancy Co-Investigator(s) / Trainee: |
Program Support Award for Canadian Transfusion Medicine and Science Research Program | $833,333.00 | ||
Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking | Principal Investigator: KLUGER, Ronald Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $192,039.00 | ||
Role of Fc receptors in antibody-mediated immune suppression | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: BERNARDO REYES, Lidice |
Postdoctoral Fellowship Program | $106,200.00 | ||
Investigation of pathophysiology, prevention and treatment of murine Transfusion Related Acute Lung Injury (TRALI) | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: McVEY, Mark |
Graduate Fellowship Program | $52,000.00 | ||
Cellular therapy to improve CD4+ T-Cell responses in humanized mice infected with HIV-1: adoptive transfer of CD4+ T-cells lacking s-Src activity | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: McCARTHY, Stephen |
Graduate Fellowship Program | $96,000.00 | ||
Impact of storage on the function of cord blood hematopoietic stem and progenitor cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: JAHAN, Suria |
Graduate Fellowship Program | $104,000.00 | ||
Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease | Principal Investigator: TRUDEL, Marie Co-Investigator(s) / Trainee: MOROY, Tarik |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $453,132.00 | ||
Release, delivery and cell programming effects of platelet microparticles and microRNAs | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: BOILARD, Eric |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $427,422.00 | ||
Understanding brain death: a multipurpose educational video aimed to a diverse public and professional audience | Principal Investigator: SHEMIE, Sam Co-Investigator(s) / Trainee: |
Small Project Funding Program | $14,000.00 | ||
Short and long-term clinical effects of blood donor characteristics in transfusion recipients | Principal Investigator: FERGUSSON, Dean Co-Investigator(s) / Trainee: ACKER, Jason P., CHASSÉ, Michael, ENGLISH, Shane, FORSTER, Alan, KNOLL, Greg, McINTYRE, Lauralyn A., SHEHATA, Nadine , van WALRAVEN, Carl, WILSON, Kumanan , TINMOUTH, Alan T. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $103,806.00 | ||
Legal and policy strategies to optimize organ donation in Alberta | Principal Investigator: TOEWS, Maeghan Co-Investigator(s) / Trainee: |
James Kreppner Fellowship Program | $150,000.00 | ||
Pathogenesis and treatment of immune thrombocytopenia: Are there fundamental differences between anti-GPlba- and anti-GPllbllla-mediated thrombocytopenia? | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $378,529.00 | ||
Microfluidic devices to measure the deformability of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: SCOTT, Mark D. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $398,301.00 | ||
Elucidation of the mechanism of IVIG-associated hemolysis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: PENDERGRAST, Jacob , CSERTI-GAZDEWICH, Christine , SHEHATA, Nadine , PAVENSKI, Katerina , LAU, Wendy , CALLUM, Jeannie , LIN, Yulia , LIEBERMAN, Lani , HANNACH, Barbara |
Intramural Research Grant Program | $393,712.00 | ||
Exploratory analyses to determine if method of donor blood processing affects outcome in transfused recipients | Principal Investigator: HEDDLE, Nancy Co-Investigator(s) / Trainee: ACKER, Jason P. , ARNOLD, Donald M. , COOK, Richard J. , EIKELBOOM, John W. , O'BRIEN, Sheila F. , WEBERT, Kathryn E. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $159,878.00 | ||
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) | Principal Investigator: KUEBLER, Wolfgang Co-Investigator(s) / Trainee: SEMPLE, John W. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | $328,712.00 | ||
Defining the components of transfusable plasma that reduce bleeding | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: PRYZDIAL, Edward, NI, Heyu |
Intramural Research Grant Program | $218,230.00 | ||
Mechanism of anti-D-like antibody-mediated amelioration of immune thrombocytopenia (ITP) | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: YU, Xiaojie (Ben) |
Postdoctoral Fellowship Program | $106,200.00 | ||
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock | Principal Investigator: PARKER, Melissa Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership New Investigator Program | $300,000.00 | ||
Transfusion options in coagulopathy: Efficacy in controlling bleeding | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: QADRI, Syed |
Postdoctoral Fellowship Program | $151,800.00 | ||
Understanding IVIg mechanism(s) of action in alleviating immune platelet destruction and thrombocytopenia | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: KAPUR, Ricky |
Postdoctoral Fellowship Program | $106,200.00 | ||
Understanding the factors that influence bacterial proliferation and biofilm formation in platelet concentrates | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: LOZA CORREA, Maria |
Postdoctoral Fellowship Program | $151,800.00 | ||
Small molecule inhibitors of phagocytosis to replace intravenous immunoglobulin (IVIG) | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: TONG, Tik Nga (Cindy) |
Graduate Fellowship Program | $52,000.00 | ||
Prospective observational study of organ deceased donor management in 3 ICUs - a pilot study (the DONATE pilot study) | Principal Investigator: MEADE, Maureen Co-Investigator(s) / Trainee: D'ARAGON, Frederick, RIBIC, Christine, SHARPE, Michael, BALL, Ian, WILLIAMSON, David, DHANANI, Sonny, HANNA, Steven |
Kenneth J. Fyke Award Program | $89,555.08 |