Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep Researchers Basic research
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases Webert K, Kelton J 2016 Aspirin and related drugs Health care providers Clinical research
Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM 2017 Am J Physiol Lung Cell Mol Physiol Researchers Basic research
Acquired Factor XIII Inhibitor in Hospitalized and Perioperative Patients: A Systematic Review of Case Reports and Case Series Tone KJ, James TE, Fergusson DA, Tinmouth A, Tay J, Avey MT, Kilty S, Lalu MM 2016 Transfus Med Rev Researchers Clinical research
Acquired hemophilia A Webert KE 2012 Semin Thromb Hemost Health care providers Other
Acquired peanut hypersensitivity following platelet transfusion Ponnampalam A, Growe G, Loftus P, Chipperfield K, Bigham M 2014 Transfus Med Health care providers Clinical research
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H 2017 Nat Commun Researchers Basic research
Activated platelets can deliver mRNA regulatory Ago2-microRNA complexes to endothelial cells via microparticles Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P 2013 Blood Researchers Basic research
Acute hemolysis after intravenous immunoglobulin amid host factors of ABO-mismatched bone marrow transplantation, inflammation, and activated mononuclear phagocytes Michelis FV, Branch DR, Scovell I, Bloch E, Pendergrast J, Lipton JH, Cserti-Gazdewich CM 2014 Transfusion Health care providers Clinical research
Acute Lung Injury Causes Asynchronous Alveolar Ventilation That Can Be Corrected by Individual Sighs Tabuchi A, Nickles HT, Kim M, Semple JW, Koch E, Brochard L, Slutsky AS, Pries AR, Kuebler WM 2015 Am J Respir Crit Care Med Health care providers Clinical research
Acute megakaryoblastic transformation from essential thrombocythemia Roshan TM, Rajput AB, Berardi P, Padmore R 2017 Hum Pathol Health care providers Clinical research
Acute phase treatment of VTE: Anticoagulation, including non-vitamin K antagonist oral anticoagulants Hillis C, Crowther MA 2015 Thromb Haemost Health care providers Clinical research
Adhesion Molecules. Ni H 2013 Mechanisms in Hematology Researchers Basic research
Adhesion of anaerobic bacteria to platelet containers Kumaran D, Kalab M, Rood IGH, de Korte D, Ramirez-Arcos S 2014 Vox Sang Blood operators Basic research
Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness Arnold DM, Lauzier F, Rabbat C, Zytaruk N, Barlow Cash B, Clarke F, Heels-Ansdell D, Guyatt G, Walter SD, Davies A, Cook DJ, PROTECT Investigators on behalf of the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Clinical Trials Group 2013 Thromb Res Researchers Clinical research
Adoptive-Transfer Effects of Intravenous Immunoglobulin in Autoimmunity Lazarus AH 2010 J Clin Immunol Researchers Basic research
Advances in umbilical cord blood stem cell expansion and clinical translation Pineault N, Abu-Khader A 2015 Exp Hematol Researchers Other
Advancing risk assessment for emerging infectious diseases for blood and blood products: proceedings of a public workshop Gallagher LM, Ganz PR, Yang H, Kessler DA, O'Brien SF, Custer BS, Busch MP, Dodd RY, Stramer SL, Walderhaug MO, Forshee RA, Williams AE, Epstein JS, Anderson SA 2013 Transfusion Blood operators Other
Adverse Reactions Callum J, Pinkerton P, Lima A, Lin Y, Karkouti K, Lieberman L, Pendergrast J, Robitaille N, Tinmouth A, Webert K 2017 Clinical Guide to Transfusion Health care providers Other
Age of transfused blood in critically ill adults Lacroix J, Hebert PC, Fergusson DA, Tinmouth A, Cook DJ, Marshall JC, Clayton L, McIntyre L, Callum J, Turgeon AF, Blajchman MA, Walsh TS, Stanworth SJ, Campbell H, Capellier G, Tiberghien P, Bardiaux L, van de Watering L, van der Meer NJ, Sabri E, Vo D 2015 N Engl J Med Health care providers Clinical research
Aggregates in platelet concentrates van der Meer PF, Dumont LJ, Lozano M, Bondar N, Wong J, Ismay S, Pink J, Nussbaumer W, Coene J, Feys HB, Compernolle V, Devine DV, Howe D, Lin CK, Sun J, Ringwald J, Strasser EF, Eckstein R, Seltsam A, Perseghin P, Proserpio P, Wakamoto S, Akino M, Takamoto S, Tadokoro K, Teo D, Shu PH, Chua SS, Jimenez-Marco T, Lozano M, Cid J, Castro E, Munoz I, Gulliksson H, Sandgren P, Thomas S, Petrik J, McColl K, Kamel H, Dugger J, Sweeney JD, Gorlin JB, Sutor LJ, Heath D, Sayers MH 2015 Vox Sang Blood operators Benchmarking and standard setting
Airway Compromise and Perioperative Management of a Patient with Acquired Factor XIII Inhibitor Tone K, Lalu M, Kilty SJ, Rosenberg E, Tinmouth A 2015 A&A Case Reports Health care providers Clinical research
Albumin Nahirniak S 2015 Clinical Guide to Transfusion Health care providers Other
Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2 Kapur R, Semple JW 2016 Ann Transl Med Researchers Basic research
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia Guo L, Yang L, Speck ER, Aslam R, Kim M, McKenzie CGJ, Lazarus AH, Ni H, Hou M, Freedman J, Semple JW 2014 Blood Researchers Basic research
Alloimmune Red Blood Cell Antibodies: Prevalence and Pathogenicity in a Canadian Prenatal Population Zwingerman R, Jain V, Hannon J, Zwingerman N, Clarke G 2015 J Obstet Gynaecol Can Health care providers Clinical research
Alloimmunization of patients by blood units harboring distinct DEL variants St-Louis M, Lebrun A, Goldman M, Lavoie M 2013 Immunohematology Health care providers Clinical research
Allowing blood donation from men who had sex with men more than 5 years ago: a model to evaluate the impact on transfusion safety in Canada Germain M, Robillard P, Delage G, Goldman M 2013 Vox Sang Blood operators New or improved product or process
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE 2014 Microcirculation Researchers Basic research
Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor Gierczak RF, Pepler L, Bhagirath V, Liaw PC, Sheffield WP 2014 Thromb Res Researchers Basic research
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA Kalathottukaren MT, Abraham L, Kapopara PR, Lai BFL, Shenoi RA, Rosell FI, Conway EM, Pryzdial ELG, Morrissey JH, Haynes CA, Kizhakkedathu JN 2016 Blood Researchers Basic research
Altered timing of riboflavin and ultraviolet light pathogen inactivation improves platelet in vitro quality Schubert P, Culibrk B, Karwal S, Serrano K, Levin E, Yi Q, Thiele T, Greinacher A, Marschner S, Devine DV 2017 Transfusion Researchers New or improved product or process
Alternative methods of blood donor skin disinfection Ramirez-Arcos S, Taha M, Kou Y, Goldman M 2017 Blood.ca website Blood operators New or improved product or process
Alternatives in blood operations when choosing non-DEHP bags van der Meer PF, Devine DV, on behalf of the BEST Collaborative 2017 Vox Sang Blood operators New or improved product or process
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K 2014 Radiology Researchers Basic research
Amelioration of murine immune thrombocytopenia by CD44 antibodies: a potential therapy for ITP? Crow AR, Song S, Suppa SJ, Ma S, Reilly MP, Andre P, McKenzie SE, Lazarus AH 2011 Blood Researchers Basic research
Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway Crow AR, Yu H, Han D, Lazarus AH 2013 PLoS One Researchers Basic research
An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches Acker JP, Croteau IM, Yi QL 2012 Clin Chim Acta Researchers New or improved product or process
An enclosed in-gel PCR amplification cassette with multi-target, multi-sample detection for platform molecular diagnostics Manage DP, Lauzon J, Atrazev A, Chavali R, Samuel RA, Chan B, Morrissey YC, Gordy W, Edwards AL, Larison K, Yanow SK, Acker JP, Zahariadis G, Pilarski LM 2013 Lab Chip Health care providers New or improved product or process
An epidemiologic cohort study reviewing the practice of blood product transfusions among a population of pediatric oncology patients Lieberman L, Liu Y, Portwine C, Barty RL, Heddle NM 2014 Transfusion Health care providers Clinical research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion Researchers Clinical research
An international investigation into AB plasma administration in hospitals: how many AB plasma units were infused? The HABSWIN study Zeller MP, Barty R, Dunbar NM, Elahie A, Flanagan P, Garritsen H, Kutner JM, Pagano MB, Poglod R, Rogers TS, Staves J, van Wordragen-Vlaswinkel M, Zwaginga JJ, Murphy MF, Heddle NM, Yazer MH 2018 Transfusion Health care providers Clinical research
An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study Zeller MP, Barty R, Aandahl A, Apelseth TO, Callum J, Dunbar NM, Elahie A, Garritsen H, Hancock H, Kutner JM, Manukian B, Mizuta S, Okuda M, Pagano MB, Poglod R, Rushford K, Selleng K, Sorensen CH, Sprogoe U, Staves J, Weiland T, Wendel S, Wood EM, van de Watering L, van Wordragen-Vlaswinkel M, Ziman A, Jan Zwaginga J, Murphy MF, Heddle NM, Yazer MH 2017 Transfusion Health care providers Clinical research
An international survey on the role of the hospital transfusion committee Yazer MH, Lozano M, Fung M, Kutner J, Murphy MF, Oveland Apelseth T, Poglod R, Selleng K, Tinmouth A, Wendel S, Yahalom V, on behalf of the BEST Collaborative 2017 Transfusion Health care providers New or improved product or process
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang Researchers Basic research
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee 2013 Am J Respir Crit Care Med Researchers Benchmarking and standard setting
Aneurysmal SubArachnoid Hemorrhage—Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol English SW, Fergusson D, Chassé M, Turgeon A, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C 2016 BMJ Open Researchers Clinical research
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis Lei X, Reheman A, Hou Y, Zhou H, Wang Y, Marshall AH, Liang C, Dai X, Li BX, Vanhoorelbeke K, Ni H 2014 Thromb Haemost Researchers Basic research
Angiogenesis and bleeding disorders in FNAIT Yougbare I, Zdravic D, Ni H 2015 Oncotarget Researchers Clinical research
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H 2010 Blood Researchers Basic research